LSD CRYSTAL FOR DUMMIES

Within the LSD-bound crystal structure, the side chain in the lid residue L209EL2 kinds in depth hydrophobic contacts with equally LSD and encompassing residues in TMs III, IV, and V (Determine 4C). Once the lid moved apart to show the binding pocket in simulation, quite a few of such contacts broke. We Therefore hypothesized that L209EL2 acts bein